A Vidi-grant for Lukas Kapitein
http://www.uu.nl/faculty/science/NL/actueel/nieuwsfaculteit/Pages/5-Vidi-subsidies-voor-Utrechtse-betawetenschappers.aspx
adm_cbweb
Dr. Myrrhe van Spronsen wins the 2013 Dutch Neurofederation PhD thesis prize
PERSBERICHT The Dutch Neurofederation is proud to announce that the winner of this year’s prize is Dr. Myrrhe van Spronsen (Utrecht University), with her thesis ‘ Motors and adaptors: transport regulation within neurons ‘ (promotor prof dr C Hoogenraad). Myrrhe will receive the prize and give a lecture at the ENP meeting in Lunteren on … Read more
Summerschool 2013 – Neuronal Circuit development and plasticity
www.utrechtsummerschool.nl
Mitochondrial Trafficking to Axons and Dendrites
Myrrhe van Spronsen, Marina Mikhaylova, Joanna Lipka, Max A. Schlager, Dave J. van den Heuvel, Marijn Kuijpers, Phebe S. Wulf, Nanda Keijzer, Jeroen Demmers, Lukas C. Kapitein, Dick Jaarsma, Hans C. Gerritsen, Anna Akhmanova, Casper C. Hoogenraad. TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites. Neuron, Volume 77, Issue 3, 485-502, 6 February … Read more
Structural basis of tubulin tyrosination by TTL
Prota AE, Magiera MM, Kuijpers M, Bargsten K, Frey D, Wieser M, Jaussi R, Hoogenraad CC, Kammerer RA, Janke C, Steinmetz MO. Structural basis of tubulin tyrosination by tubulin tyrosine ligase. J Cell Biol. 2013 Feb 4;200(3):259-70. doi: 10.1083/jcb.201211017. Epub 2013 Jan 28. Tubulin tyrosine ligase (TTL) catalyzes the post-translational retyrosination of detyrosinated α-tubulin. Despite … Read more
BICD2 brings dynein and dynactin together
Splinter D, Razafsky DS, Schlager MA, Serra-Marques A, Grigoriev I, Demmers J, Keijzer N, Jiang K, Poser I, Hyman AA, Hoogenraad CC, King SJ, Akhmanova A. BICD2, dynactin and LIS1 cooperate in regulating dynein recruitment to cellular structures. Mol Biol Cell. 2012 Sep 5.PMID:22956769 Cytoplasmic dynein is the major microtubule minus-end directed cellular motor. Most … Read more
DNERR in paraneoplastic cerebellar degeneration
Identification of Delta/Notch-like Epidermal Growth Factor-Related Receptor as the Tr Antigen in Paraneoplastic Cerebellar Degeneration. Esther de Graaff, Peter Maat, Esther Hulsenboom, Robert van den Berg, Martin van den Bent, Jeroen Demmers, Pieternella J. Lugtenburg, Casper C. Hoogenraad and Peter Sillevis Smitt Annals of Neurology 2012 71(6):815-24. PMID: 22447725 [Epub 2012 Feb 1]. Paraneoplastic cerebellar … Read more
Proteome-wide search reveals multiple new +TIPs
Jiang K, Toedt G, Montenegro Gouveia S, Davey NE, Hua S, van der Vaart B, Grigoriev I, Larsen J, Pedersen LB, Bezstarosti K, Lince-Faria M, Demmers J, Steinmetz MO, Gibson TJ, Akhmanova A. A Proteome-wide Screen for Mammalian SxIP Motif-Containing Microtubule Plus-End Tracking Proteins. Curr Biol. 2012 Oct 9;22(19):1800-7. PMID:22885064 Microtubule plus-end tracking proteins (+TIPs) … Read more